| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Paradigm Biocapital Advisors Senai Asefaw | 8,020,576 | $119,586,788 | +7% | 2.44% |
| 2. | Biotechnology Value Fund / BVF Inc Mark Lampert | 5,295,893 | $78,961,765 | 2.52% | |
| 3. | Siren L.L.C. Raymond Debbane | 4,756,949 | $70,926,110 | +45% | 1.97% |
| 4. | Cormorant Asset Management Bihua Chen | 3,900,000 | $58,149,000 | +42% | 2.92% |
| 5. | Logos Capital Arsani William | 3,208,875 | $47,844,326 | 2.39% |