| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Paradigm Biocapital Advisors Senai Asefaw | 8,670,576 | $108,468,906 | +9% | 2.03% |
| 2. | Biotechnology Value Fund / BVF Inc Mark Lampert | 5,295,893 | $66,251,621 | 1.69% | |
| 3. | Siren L.L.C. Raymond Debbane | 4,856,949 | $60,760,432 | +3% | 1.23% |
| 4. | Logos Capital Arsani William | 3,208,875 | $40,143,026 | 1.73% | |
| 5. | Cormorant Asset Management Bihua Chen | 2,150,000 | $26,896,500 | -45% | 1.38% |