| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Deerfield Management James E. Flynn | 17,248,450 | $1,767,103,703 | 20.85% | |
| 2. | Paradigm Biocapital Advisors Senai Asefaw | 5,324,433 | $545,488,161 | +2% | 11.15% |
| 3. | RA Capital Management Peter Kolchinsky | 2,534,145 | $259,623,155 | +35% | 2.75% |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 1,831,253 | $187,611,870 | +20% | 0.67% |
| 5. | Perceptive Advisors Joseph Edelman | 1,580,505 | $161,922,737 | -6% | 3.16% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $33.50 | 650,000 | $21,775,000.00 | 650,000 | 2022-11-03 | Filing | |
| $33.50 | 149,253 | $4,999,975.50 | 3,577,267 | 2022-11-03 | Filing | |
| $17.00 | 735,000 | $12,495,000.00 | 3,428,014 | 2021-08-02 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $123.59 | 23,000 | $2,842,570.00 | 58,117 | 2026-07-01 | Filing | |
| $123.58 | 11,430 | $1,412,519.40 | 85,533 | 2026-07-01 | Filing | |
| $123.51 | 5,500 | $679,305.00 | 58,117 | 2026-06-29 | Filing | |
| $122.81 | 20,000 | $2,456,200.00 | 58,117 | 2026-06-09 | Filing | |
| $89.63 | 3,036 | $272,116.68 | 324,879 | 2026-06-08 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 604 | $74,594 | 0% | |
| 2. | 84 | $10,374 | 0% | |
| 3. | 11 | $1,359 | 0% | |
| 4. | 2 | $247 | 0% |
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