| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 72,800 | $6,173 | 0.77% | |
| 2. | Birchview Capital Matthew Strobeck | 8,000 | $678 | 0.39% | |
| 3. | Point72 Asset Management Steve Cohen | 684,025 | $58,005 | 0.25% | |
| 4. | Clinton Group George Hall | 34,299 | $2,909 | -55% | 0.25% |
| 5. | DAFNA Capital Management Nathan Fischel | 5,000 | $424 | 0.22% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.38 | 1,000 | Director | 1,000 | 2012-06-01 | Filing | |
| $18.47 | 50,000 | Officer, Director | 2,830,291 | 2012-06-01 | Filing | |
| $18.00 | 7,000 | Officer | 10,524 | 2011-11-21 | Filing | |
| $18.28 | 35,404 | Officer, Director | 2,780,291 | 2011-11-22 | Filing | |
| $20.24 | 64,596 | Officer, Director | 4,177,096 | 2011-10-28 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $87.50 | 12,000 | Officer | 9,201 | 2018-03-29 | Filing | |
| $87.50 | 6,000 | Officer | 9,201 | 2018-03-29 | Filing | |
| $87.50 | 11,303 | Officer | 9,201 | 2018-03-29 | Filing | |
| $86.02 | 2,000 | Director | 66,249 | 2018-04-02 | Filing | |
| $90.00 | 100 | Officer | 71,000 | 2018-03-13 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 137,785 | $12,118 | 1.01% | |
| 2. | 21,159 | $1,861 | 0.76% | |
| 3. | 13,711 | $1,206 | 0.51% | |
| 4. | 324,242 | $28,517 | 0.43% | |
| 5. | 17,616 | $1,549 | 0.37% |
