| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Healthcor Management LP Arthur B Cohen And Joseph Healey | 747,040 | $72,948 | +30% | 2.31% |
| 2. | Birchview Capital Matthew Strobeck | 8,000 | $781 | 0.53% | |
| 3. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 42,201 | $4,121 | -43% | 0.46% |
| 4. | Marshall Wace LLP Paul Marshall And Ian Wace | 588,509 | $57,468 | -5% | 0.32% |
| 5. | LMR Partners Ben Levine, Andrew Manuel And Stefan Renold | 64,074 | $6,257 | 0.32% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.38 | 1,000 | Director | 1,000 | 2012-06-01 | Filing | |
| $18.47 | 50,000 | Officer, Director | 2,830,291 | 2012-06-01 | Filing | |
| $18.00 | 7,000 | Officer | 10,524 | 2011-11-21 | Filing | |
| $18.28 | 35,404 | Officer, Director | 2,780,291 | 2011-11-22 | Filing | |
| $20.24 | 64,596 | Officer, Director | 4,177,096 | 2011-10-28 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $110.00 | 10,000 | Director | 64,832 | 2018-08-09 | Filing | |
| $109.03 | 30,801 | Officer, Director | 139,241 | 2018-08-06 | Filing | |
| $109.08 | 29,273 | Officer, Director | 139,241 | 2018-08-02 | Filing | |
| $101.00 | 2,000 | Director | 57,832 | 2018-08-01 | Filing | |
| $100.00 | 2,000 | Director | 59,832 | 2018-07-06 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 43,325 | $4,231 | 2.96% | |
| 2. | 81,277 | $7,937 | 1.87% | |
| 3. | 249,543 | $24,368 | 1.75% | |
| 4. | 27,476 | $2,683 | 1.69% | |
| 5. | 20,000 | $1,953 | 1.65% |
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