| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Vivo Capital Albert Cha And Frank Kung | 1,359,149 | $30,105 | 2.82% | |
| 2. | Samsara BioCapital Srini Akkaraju And Michael Dybbs | 118,500 | $2,625 | 1.73% | |
| 3. | Ghost Tree Capital Ken Greenberg And David Kim | 300,000 | $6,645 | -25% | 1.39% |
| 4. | Deerfield Management James E. Flynn | 1,217,668 | $26,971 | +88% | 0.96% |
| 5. | Polar Capital Brian Ashford-Russell And Tim Woolley | 1,387,500 | $30,733 | +21% | 0.26% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $11.87 | 7,962 | Director | 10,000 | 2019-09-27 | Filing | |
| $11.90 | 2,038 | Director | 2,038 | 2019-09-26 | Filing | |
| $17.13 | 5,137 | Director | 124,566 | 2019-07-29 | Filing | |
| $17.13 | 24,730 | Director | 1,022,493 | 2019-07-29 | Filing | |
| $16.83 | 21,942 | Director | 997,763 | 2019-07-26 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.35 | 7,355 | Officer | 82,969 | 2019-07-22 | Filing | |
| $18.65 | 1,900 | Officer | 96,734 | 2019-07-23 | Filing | |
| $18.57 | 1,400 | Officer | 98,634 | 2019-07-22 | Filing | |
| $17.04 | 10,000 | Officer, Director | 248,510 | 2019-07-15 | Filing | |
| $26.79 | 1,000 | Officer | 82,969 | 2019-04-22 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 1,719,576 | $38,088 | 25.56% | |
| 2. | 637,884 | $14,129 | 6.59% | |
| 3. | 388,766 | $8,611 | 2.78% | |
| 4. | 376,889 | $8,348 | 2.63% | |
| 5. | 213,000 | $4,718 | 1.67% |
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