| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 765,297.2 | $8,494,799 | 0.27% | |
| 2. | Avidity Partners Management David Witzke And Michael Gregory | 669,941.1 | $7,436,346 | +43% | 1.47% |
| 3. | Soleus Capital Guy Levy | 450,000 | $4,995,000 | 0.2% | |
| 4. | Laurion Capital Management Benjamin A. Smith | 388,216.2 | $4,309,200 | 0.19% | |
| 5. | Millennium Management Israel Englander | 377,992.2 | $4,195,713 | +11% | 0% |