| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | 5,500,000 | $6,493 | 4.62% | ||
| 2. | Hitchwood Capital Management James Crichton | 444,458 | $124,133 | +9% | 3.89% |
| 3. | Opus Point Partners Management Michael S. Weiss And Lindsay A. Rosenwald | 5,352 | $1,495 | -3% | 3.24% |
| 4. | Casdin Capital Eli Casdin | 71,500 | $19,969 | 2.9% | |
| 5. | Waterstone Capital Management Shawn Bergerson And Martin Kalish | 10,161 | $2,838 | 2.9% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $43.87 | 315 | Director | 670 | 2012-04-18 | Filing | |
| $36.54 | 809 | Director | 809 | 2012-01-17 | Filing | |
| $61.68 | 240 | Director | 1,248 | 2011-07-29 | Filing | |
| $71.37 | 99 | Director | 1,008 | 2011-05-03 | Filing | |
| $71.56 | 169 | Director | 909 | 2011-05-02 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $333.10 | 200 | Officer | 70,805 | 2018-08-10 | Filing | |
| $332.32 | 3,737 | Officer | 71,005 | 2018-08-10 | Filing | |
| $331.38 | 2,600 | Officer | 74,742 | 2018-08-10 | Filing | |
| $330.29 | 3,463 | Officer | 77,342 | 2018-08-10 | Filing | |
| $320.70 | 1,334 | Officer | 24,484 | 2018-08-02 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 82,049 | $22,915 | 11.87% | |
| 2. | 12,250,000 | $14,391 | 11.2% | |
| 3. | 41,124 | $11,486 | 8.33% | |
| 4. | 52,640 | $14,702 | 7.71% | |
| 5. | 20,464,000 | $24,096 | 7.43% |
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