| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Broadfin Capital Kevin Kotler | 3,018,021 | $44,063 | -3% | 7.2% |
| 2. | Scopia Capital Matt Sirovich And Jeremy Mindich | 16,370,364 | $239,007 | +2% | 4.28% |
| 3. | VenBio Select Advisor Kurt Von Emster | 4,436,183 | $64,768 | +27% | 4.19% |
| 4. | Deerfield Management James E. Flynn | 6,341,894 | $92,592 | -9% | 3.64% |
| 5. | Paulson & Co John Paulson | 7,870,700 | $114,912 | +42% | 2.24% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $9.48 | 10,000 | Director | 25,448 | 2017-05-10 | Filing | |
| $31.32 | 10,000 | Director | 10,000 | 2015-08-19 | Filing | |
| $9.76 | 6,000 | Director | 6,000 | 2014-08-14 | Filing | |
| $6.50 | 32,075 | Director | 178,406 | 2013-12-13 | Filing | |
| $6.50 | 32,075 | Director | 178,478 | 2013-12-13 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $16.00 | 30,000 | Officer | 95,408 | 2017-03-01 | Filing | |
| $16.48 | 1,808 | Officer | 125,408 | 2017-02-28 | Filing | |
| $20.00 | 2,900 | Officer | 159,250 | 2016-08-02 | Filing | |
| $17.69 | 25,000 | Director | 189,836 | 2016-06-15 | Filing | |
| $20.00 | 4,456 | Officer | 105,132 | 2015-12-10 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 2,007,212 | $28,502 | 3.51% | |
| 2. | 51,276 | $728 | 0.39% | |
| 3. | 28,727 | $408 | 0.09% | |
| 4. | 6,200 | $88 | 0% | |
| 5. | 3,832 | $54 | 0% |
