| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 2,252,987 | $14,464,177 | 0.29% | |
| 2. | Opaleye Management James A. Silverman | 1,256,228 | $8,064,984 | +489% | 1.06% |
| 3. | Renaissance Technologies Jim Simons | 206,915 | $1,328,394 | +108% | 0% |
| 4. | Marshall Wace LLP Paul Marshall And Ian Wace | 52,440 | $336,664 | 0% | |
| 5. | Two Sigma Advisors John Overdeck And David Siegel | 42,346 | $271,861 | 0% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $22.50 | 533,333 | $11,999,992.50 | 1,158,333 | 2019-04-12 | Filing | |
| $16.00 | 625,000 | $10,000,000.00 | 625,000 | 2018-04-02 | Filing | |
| $16.00 | 625,000 | $10,000,000.00 | 2,613,517 | 2018-04-02 | Filing | |
| $16.00 | 250,000 | $4,000,000.00 | 645,845 | 2018-04-02 | Filing | |
| $16.00 | 375,000 | $6,000,000.00 | 770,845 | 2018-04-02 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.51 | 3,995 | $18,035.03 | 35,943 | 2026-02-25 | Filing | |
| $4.51 | 9,896 | $44,674.50 | 89,104 | 2026-02-25 | Filing | |
| $4.51 | 2,815 | $12,708.04 | 55,569 | 2026-02-25 | Filing | |
| $3.46 | 22,506 | $77,870.76 | 99,000 | 2025-12-02 | Filing | |
| $3.46 | 9,072 | $31,395.47 | 39,938 | 2025-12-02 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 2,092,106 | $13,431,321 | 1.7% | |
| 2. | 1,102,741 | $7,079,597 | 0.07% | |
| 3. | 320,482 | $2,057,494 | 0.3% | |
| 4. | 315,052 | $2,022,634 | 0.57% | |
| 5. | 306,401 | $1,967,094 | 0% |