| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 5,842,100 | $368,811 | -4% | 5.97% |
| 2. | Great Point Partners Jeffrey Jay And David Kroin | 542,200 | $34,229 | 2.73% | |
| 3. | Marshall Wace LLP Paul Marshall And Ian Wace | 535,276 | $33,792 | +529% | 0.22% |
| 4. | Millennium Management Israel Englander | 308,652 | $19,485 | +3945% | 0.02% |
| 5. | Casdin Capital Eli Casdin | 300,000 | $18,939 | 1.12% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $52.37 | 10,000 | Director | 31,428 | 2020-03-13 | Filing | |
| $38.00 | 175,000 | Large Shareholder | 4,889,066 | 2017-12-19 | Filing | |
| $20.00 | 25,000 | Officer | 25,000 | 2015-08-17 | Filing | |
| $22.36 | 1,000 | Officer | 1,500 | 2016-01-07 | Filing | |
| $20.00 | 500 | Officer | 500 | 2015-08-17 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $63.77 | 2,200 | Officer | 5,244 | 2020-08-20 | Filing | |
| $70.10 | 950 | Officer | 0 | 2020-08-05 | Filing | |
| $69.32 | 1,504 | Officer | 950 | 2020-08-05 | Filing | |
| $75.00 | 15,208 | Officer | 3,048 | 2020-07-13 | Filing | |
| $64.42 | 881 | Director | 2,256 | 2020-06-19 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 72,261 | $4,561,838 | 0% | |
| 2. | 16,989 | $1,072,516 | 0% | |
| 3. | 9,140,454 | $577,038 | 0.06% | |
| 4. | 5,519,586 | $348,451 | 0.01% | |
| 5. | 5,483,250 | $346,158 | 0.05% |
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