| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Ghost Tree Capital Ken Greenberg And David Kim | 3,525,000 | $1,011 | 0.35% | |
| 2. | Vivo Capital Albert Cha And Frank Kung | 8,180,000 | $2,346 | 0.29% | |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 5,114,455 | $1,467 | -3% | 0.19% |
| 4. | Millennium Management Israel Englander | 70,068 | $20 | -88% | 0% |
| 5. | BlueCrest Capital Mgmt. Michael Platt And William Reeves | 0 | $0 | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $0.47 | 9,948,269 | Large Shareholder | 34,948,269 | 2019-02-14 | Filing | |
| $0.47 | 9,948,269 | Large Shareholder | 34,948,269 | 2019-02-14 | Filing | |
| $0.47 | 9,948,269 | Large Shareholder | 34,948,269 | 2019-02-14 | Filing | |
| $0.47 | 9,948,269 | Large Shareholder | 34,948,269 | 2019-02-14 | Filing | |
| $0.47 | 9,948,269 | Large Shareholder | 34,948,269 | 2019-02-14 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $6.00 | 45,000 | Officer | 39,247 | 2017-07-24 | Filing | |
| $6.51 | 6,213 | Officer | 42,747 | 2017-05-08 | Filing | |
| $11.35 | 2,229 | Officer | 1,881 | 2015-09-01 | Filing | |
| $13.05 | 2,229 | Officer | 1,881 | 2015-08-03 | Filing | |
| $13.92 | 2,229 | Officer | 1,881 | 2015-07-01 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,000 | $1 | 0% | |
| 2. | 19,360 | $11 | 0% | |
| 3. | 0 | $0 | 0% |
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