| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 1,577,705 | $33,526,231 | +32% | 0.62% |
| 2. | BioImpact Capital Mpm Capital | 987,448 | $20,983,270 | -2% | 1.28% |
| 3. | Woodline Partners Michael Rockefeller And Karl Kroeker | 712,753 | $15,146,001 | +115% | 0.05% |
| 4. | Adage Capital Management Phill Gross And Robert Atchinson | 700,000 | $14,875,000 | -27% | 0.02% |
| 5. | Integral Health Asset Management Bhagwan Jay Rao | 675,000 | $14,343,750 | +350% | 0.57% |