| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Ako Capital Nicolai Tangen | 828,423 | $193,263 | +29% | 4.15% |
| 2. | Giverny Capital Francois Rochon | 128,515 | $29,981 | +2% | 2.71% |
| 3. | OrbiMed Advisors Samuel Isaly | 434,900 | $101,458 | -15% | 1.44% |
| 4. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 183,500 | $42,809 | 1.35% | |
| 5. | Sivik Global Healthcare Krishen Sud | 15,000 | $3,499 | -40% | 1.29% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $90.10 | 3,000 | Director | 9,042 | 2017-02-03 | Filing | |
| $83.33 | 3,942 | Officer | 3,942 | 2016-11-30 | Filing | |
| $83.47 | 8,928 | Officer | 43,690 | 2016-11-30 | Filing | |
| $84.63 | 3,000 | Director | 6,042 | 2016-11-29 | Filing | |
| $101.07 | 5,000 | Director | 5,000 | 2016-05-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $228.57 | 2,500 | Officer | 16,889 | 2020-02-18 | Filing | |
| $230.85 | 7,794 | Officer, Director | 47,126 | 2020-02-10 | Filing | |
| $227.76 | 5,300 | Officer, Director | 54,920 | 2020-02-10 | Filing | |
| $228.56 | 4,149 | Officer, Director | 60,220 | 2020-02-10 | Filing | |
| $230.04 | 4,100 | Officer, Director | 64,369 | 2020-02-10 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 65,258 | $15,224 | 6.25% | |
| 2. | 20,129 | $4,696 | 5.13% | |
| 3. | 562,705 | $131,273 | 4.93% | |
| 4. | 28,144 | $6,566 | 4.86% | |
| 5. | 63,804 | $14,885 | 4.66% |
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