| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | ADAR1 Capital Management Daniel Schneeberger | 8,889,000 | $28,800,360 | 1.32% | |
| 2. | RA Capital Management Peter Kolchinsky | 8,889,000 | $28,800,360 | 0.25% | |
| 3. | Commodore Capital Egen Atkinson And Michael Kramarz | 8,889,000 | $28,800,360 | 1.72% | |
| 4. | Paradigm Biocapital Advisors Senai Asefaw | 5,586,625 | $18,100,665 | 0.34% | |
| 5. | Opaleye Management James A. Silverman | 3,861,930 | $12,512,653 | +101% | 1.13% |