| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 15,518,492 | $251,709,940 | 5.92% | |
| 2. | RA Capital Management Peter Kolchinsky | 10,428,437 | $169,149,248 | +6% | 2.08% |
| 3. | Baker Bros. Advisors Julian Baker And Felix Baker | 7,305,940 | $118,502,347 | 0.86% | |
| 4. | Braidwell LP Alex Karnal | 5,210,831 | $84,519,679 | 2.51% | |
| 5. | Cormorant Asset Management Bihua Chen | 4,010,000 | $65,042,200 | -6% | 4.49% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.64 | 10,700 | $199,403.06 | 23,702 | 2025-11-11 | Filing | |
| $20.13 | 124,193 | $2,500,005.09 | 443,792 | 2025-04-03 | Filing | |
| $20.13 | 372,578 | $7,499,995.14 | 14,809,075 | 2025-04-03 | Filing | |
| $20.13 | 124,193 | $2,500,005.09 | 443,792 | 2025-04-03 | Filing | |
| $20.13 | 372,578 | $7,499,995.14 | 14,809,075 | 2025-04-03 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $21.12 | 100,000 | $2,112,450.00 | 23,400 | 2025-11-12 | Filing | |
| $14.60 | 100,000 | $1,459,760.00 | 23,400 | 2025-08-26 | Filing | |
| $13.39 | 2,098 | $28,097.26 | 10,214 | 2025-08-12 | Filing | |
| $13.39 | 2,491 | $33,360.47 | 23,645 | 2025-08-12 | Filing | |
| $13.39 | 1,428 | $19,124.35 | 86,162 | 2025-08-12 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 6,351,487 | $103,021,118 | 0% | |
| 2. | 6,170,131 | $100,079,525 | 2.85% | |
| 3. | 5,350,000 | $86,777,000 | 5.59% | |
| 4. | 4,979,331 | $80,804,202 | 0.04% | |
| 5. | 4,803,941 | $77,919,924 | 0% |
