| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Columbus Circle Investors Principal Global Investors | 496,369 | $74,078 | -14% | 2.71% |
| 2. | Pura Vida Investments Efrem Kamen | 45,000 | $6,716 | -28% | 2.35% |
| 3. | Great Point Partners Jeffrey Jay And David Kroin | 151,264 | $22,575 | 2.07% | |
| 4. | Eversept Partners Kamran Moghtaderi | 44,550 | $6,649 | 2.07% | |
| 5. | DAFNA Capital Management Nathan Fischel | 36,338 | $5,423 | 2.03% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $50.01 | 25,000 | Director | 58,502 | 2017-11-07 | Filing | |
| $49.61 | 10,000 | Director | 33,502 | 2017-11-06 | Filing | |
| $15.50 | 70,000 | Director | 121,975 | 2013-03-11 | Filing | |
| $10.37 | 1,000 | Director | 6,000 | 2012-03-08 | Filing | |
| $10.34 | 1,000 | Director | 5,000 | 2012-03-08 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $226.51 | 400 | Officer | 27,447 | 2019-12-09 | Filing | |
| $225.55 | 1,219 | Officer | 27,847 | 2019-12-09 | Filing | |
| $224.36 | 1,999 | Officer | 29,066 | 2019-12-09 | Filing | |
| $223.31 | 1,900 | Officer | 31,065 | 2019-12-09 | Filing | |
| $228.93 | 462 | Director | 16,147 | 2019-12-03 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 9,000,000 | $14,319 | 6.38% | |
| 2. | 2,561 | $382 | 5.92% | |
| 3. | 14,770 | $2,204 | 4.72% | |
| 4. | 40,584 | $6,057 | 3.96% | |
| 5. | 34,540 | $5,154,819 | 3.15% |
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