| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Bridger Management Roberto Mignone | 671,005 | $63,732 | -26% | 3.45% |
| 2. | DAFNA Capital Management Nathan Fischel | 55,000 | $5,224 | -27% | 2.44% |
| 3. | Pura Vida Investments Efrem Kamen | 25,000 | $2,375 | -33% | 2.01% |
| 4. | Healthcor Management LP Arthur B Cohen And Joseph Healey | 614,630 | $58,378 | 1.85% | |
| 5. | Atika Capital Brad Farber | 75,000 | $7,124 | +135% | 1.36% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $50.01 | 25,000 | Director | 58,502 | 2017-11-07 | Filing | |
| $49.61 | 10,000 | Director | 33,502 | 2017-11-06 | Filing | |
| $15.50 | 70,000 | Director | 121,975 | 2013-03-11 | Filing | |
| $10.37 | 1,000 | Director | 6,000 | 2012-03-08 | Filing | |
| $10.34 | 1,000 | Director | 5,000 | 2012-03-08 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $124.24 | 1,178 | Officer, Director | 335,171 | 2018-08-13 | Filing | |
| $123.65 | 5,535 | Officer, Director | 336,349 | 2018-08-13 | Filing | |
| $122.41 | 4,448 | Officer, Director | 341,884 | 2018-08-13 | Filing | |
| $125.18 | 2,300 | Officer | 33,680 | 2018-08-10 | Filing | |
| $124.36 | 7,500 | Officer | 35,980 | 2018-08-10 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,598 | $342 | 5.89% | |
| 2. | 290,204 | $27,564 | 3.66% | |
| 3. | 51,110 | $4,854 | 2.98% | |
| 4. | 270,897 | $25,730 | 2.19% | |
| 5. | 606,534 | $57,584 | 2.11% |
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