| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 4,999,999 | $425,949,915 | +50% | 3.82% |
| 2. | Polar Capital Brian Ashford-Russell And Tim Woolley | 2,253,649 | $191,988,358 | +36% | 0.45% |
| 3. | Integral Health Asset Management Bhagwan Jay Rao | 1,600,000 | $136,304,000 | 5.38% | |
| 4. | Point72 Asset Management Steve Cohen | 1,587,712 | $135,257,185 | +154% | 0.15% |
| 5. | 1,530,000 | $130,340,700 | -10% | 1.59% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.57 | 6,000 | $51,426.60 | 6,250 | 2019-11-19 | Filing | |
| $9.52 | 8,506 | $80,934.59 | 499,312 | 2019-12-11 | Filing | |
| $9.52 | 49,804 | $473,885.06 | 2,861,622 | 2019-12-11 | Filing | |
| $9.52 | 60,103 | $571,880.05 | 3,617,776 | 2019-12-11 | Filing | |
| $9.40 | 15,030 | $141,282.00 | 490,806 | 2019-12-10 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $74.66 | 1,000 | $74,660.00 | 9,184 | 2026-09-11 | Filing | |
| $75.46 | 3,500 | $264,110.00 | 153,902 | 2026-09-08 | Filing | |
| $71.48 | 5,000 | $357,400.00 | 10,784 | 2026-09-01 | Filing | |
| $70.24 | 10,000 | $702,400.00 | 58,555 | 2026-08-31 | Filing | |
| $70.24 | 7,500 | $526,800.00 | 377,820 | 2026-08-31 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 20,094,362 | $1,711,838,738 | 0.03% | |
| 2. | 6,931,770 | $590,517,486 | 0.1% | |
| 3. | 6,711,799 | $571,778,157 | 0.03% | |
| 4. | 6,494,233 | $553,243,709 | 0.02% | |
| 5. | 6,117,515 | $521,151,103 | 0.01% |
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