| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 7,206,458 | $76,461 | +74% | 5.79% |
| 2. | DAFNA Capital Management Nathan Fischel | 418,727 | $4,443 | 1.52% | |
| 3. | Driehaus Capital Richard Driehaus | 3,039,256 | $32,247 | +12% | 0.85% |
| 4. | Eversept Partners Kamran Moghtaderi | 181,700 | $1,928 | 0.37% | |
| 5. | Point72 Asset Management Steve Cohen | 3,028,751 | $32,135 | +598% | 0.16% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.57 | 6,000 | Director | 6,250 | 2019-11-19 | Filing | |
| $9.52 | 8,506 | Large Shareholder | 499,312 | 2019-12-11 | Filing | |
| $9.52 | 49,804 | Large Shareholder | 2,861,622 | 2019-12-11 | Filing | |
| $9.52 | 60,103 | Large Shareholder | 3,617,776 | 2019-12-11 | Filing | |
| $9.40 | 15,030 | Large Shareholder | 490,806 | 2019-12-10 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.82 | 8,000 | Director | 20,000 | 2020-03-06 | Filing | |
| $15.79 | 74,893 | Large Shareholder | 424,419 | 2020-02-13 | Filing | |
| $15.79 | 510,793 | Large Shareholder | 2,350,829 | 2020-02-13 | Filing | |
| $15.79 | 486,344 | Large Shareholder | 3,131,432 | 2020-02-13 | Filing | |
| $12.96 | 4,950 | Officer, Director | 224,107 | 2020-01-15 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 2,398,970 | $25,453 | 10.98% | |
| 2. | 875,656 | $9,291 | 2.1% | |
| 3. | 85,172 | $904 | 1.62% | |
| 4. | 102,476 | $1,087 | 0.43% | |
| 5. | 54,216 | $575 | 0.39% |
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