| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 4,878,035 | $101,366 | +47% | 3.98% |
| 2. | 40,050,000 | $86,262 | +12% | 0.02% | |
| 3. | Driehaus Capital Richard Driehaus | 3,226,567 | $67,048 | +7% | 1.08% |
| 4. | Deerfield Management James E. Flynn | 2,461,000 | $51,140 | 1.01% | |
| 5. | Farallon Capital Thomas Steyer | 2,400,000 | $49,872 | +12% | 0.32% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $8.57 | 6,000 | Director | 6,250 | 2019-11-19 | Filing | |
| $9.52 | 8,506 | Large Shareholder | 499,312 | 2019-12-11 | Filing | |
| $9.52 | 49,804 | Large Shareholder | 2,861,622 | 2019-12-11 | Filing | |
| $9.52 | 60,103 | Large Shareholder | 3,617,776 | 2019-12-11 | Filing | |
| $9.40 | 15,030 | Large Shareholder | 490,806 | 2019-12-10 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $23.56 | 5,000 | Officer, Director | 356,859 | 2021-04-12 | Filing | |
| $24.50 | 4,375 | Director | 920 | 2021-04-09 | Filing | |
| $23.79 | 5,000 | Director | 920 | 2021-04-09 | Filing | |
| $23.79 | 5,000 | Director | 920 | 2021-04-09 | Filing | |
| $23.80 | 5,000 | Director | 920 | 2021-04-09 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 47,970 | $1,115 | 0.01% | |
| 2. | 10,200 | $237 | 0.02% | |
| 3. | 9,715 | $226 | 0.09% | |
| 4. | 3,417 | $79 | 0% | |
| 5. | 326 | $8 | 0% |
