| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 6,767,584 | $14,280 | 0.23% | |
| 2. | Adams Street Partners Jeffrey Diehl | 3,275,616 | $6,912 | 1.72% | |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 2,156,740 | $4,551 | +33% | 0.42% |
| 4. | Millennium Management Israel Englander | 1,031,759 | $2,177 | +29% | 0% |
| 5. | Renaissance Technologies Jim Simons | 930,700 | $1,964 | +3% | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.00 | 14,736 | Officer, Director | 1,178,515 | 2019-11-13 | Filing | |
| $2.90 | 272 | Officer, Director | 1,163,779 | 2019-11-12 | Filing | |
| $3.51 | 142,656 | Large Shareholder, Director | 6,767,584 | 2019-08-06 | Filing | |
| $3.51 | 142,656 | Large Shareholder, Director | 6,767,584 | 2019-08-06 | Filing | |
| $3.54 | 2,500 | Officer, Director | 1,163,507 | 2019-08-07 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $5.37 | 741,440 | Large Shareholder | 1,389,498 | 2020-07-08 | Filing | |
| $5.25 | 796,622 | Large Shareholder | 2,130,938 | 2020-07-07 | Filing | |
| $4.00 | 1,400,000 | Large Shareholder | 2,927,560 | 2019-07-25 | Filing | |
| $5.01 | 53,240 | Large Shareholder | 4,327,560 | 2019-07-24 | Filing | |
| $5.32 | 39,716 | Large Shareholder | 4,380,800 | 2019-07-23 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 13,158 | $36 | 0% | |
| 2. | 719 | $2 | 0% | |
| 3. | 1 | $0 | 0% | |
| 4. | 0 | $0 | 0% | |
| 5. | 0 | $0 | 0% |
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