| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 21,960,850 | $50,071 | 0.92% | |
| 2. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 5,333,188 | $12,160 | +1% | 0.31% |
| 3. | Adage Capital Management Phill Gross And Robert Atchinson | 4,606,600 | $10,503 | +5% | 0.02% |
| 4. | Avidity Partners Management David Witzke And Michael Gregory | 2,000,000 | $4,560 | 0.09% | |
| 5. | Vivo Capital Albert Cha And Frank Kung | 2,000,000 | $4,560 | 0.5% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.21 | 402,000 | Large Shareholder, Director | 15,219,994 | 2022-11-08 | Filing | |
| $3.21 | 402,000 | Large Shareholder, Director | 15,219,994 | 2022-11-08 | Filing | |
| $2.32 | 10,000 | Officer, Director | 5,431,873 | 2022-09-28 | Filing | |
| $2.27 | 15,000 | Officer, Director | 5,421,873 | 2022-09-26 | Filing | |
| $3.03 | 15,000 | Officer, Director | 5,406,873 | 2022-09-07 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.36 | 2 | Officer | 1,060,414 | 2022-11-25 | Filing | |
| $4.30 | 9,569 | Officer | 1,060,416 | 2022-11-23 | Filing | |
| $4.19 | 14,929 | Officer | 1,069,985 | 2022-11-22 | Filing | |
| $4.34 | 16,035 | Officer | 1,084,914 | 2022-11-21 | Filing | |
| $4.40 | 6,226 | Officer | 1,107,175 | 2022-11-18 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 6,354,814 | $14,489 | 0% | |
| 2. | 4,400,000 | $10,032 | 7.71% | |
| 3. | 3,522,980 | $8,068 | 0% | |
| 4. | 2,829,712 | $6,452 | 1.73% | |
| 5. | 2,380,623 | $5,428 | 0% |
