| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Opaleye Management James A. Silverman | 1,750,000 | $29,225 | 10.9% | |
| 2. | Casdin Capital Eli Casdin | 2,025,000 | $33,818 | 5.78% | |
| 3. | Prescott Group Capital Management Phil Frohlich | 1,256,461 | $20,983 | +7% | 4.1% |
| 4. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 6,549,800 | $109,382 | -2% | 3.59% |
| 5. | Sensato Capital Management Ernest Chow And Jonathan Howe | 179,927 | $3,005 | -16% | 0.79% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.98 | 10,000 | Director | 348,234 | 2015-08-21 | Filing | |
| $4.83 | 10,000 | Director | 320,340 | 2016-11-15 | Filing | |
| $3.47 | 10,000 | Director | 290,246 | 2015-09-11 | Filing | |
| $3.84 | 10,000 | Director | 280,246 | 2015-08-24 | Filing | |
| $3.97 | 20,000 | Director | 270,246 | 2015-08-14 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $21.69 | 8,957 | Officer | 133,402 | 2019-02-12 | Filing | |
| $21.57 | 8,958 | Officer | 142,359 | 2019-02-11 | Filing | |
| $17.11 | 40,000 | Officer | 134,453 | 2019-01-25 | Filing | |
| $16.74 | 35,000 | Officer | 134,453 | 2019-01-24 | Filing | |
| $15.98 | 12,500 | Director | 103,093 | 2018-12-28 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,350,000 | $55,945 | 11.49% | |
| 2. | 2,714,458 | $45,331 | 5.78% | |
| 3. | 1,059,359 | $17,691 | 2.82% | |
| 4. | 232,564 | $3,884 | 1.05% | |
| 5. | 107,743 | $1,799 | 0.98% |
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