| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Opaleye Management James A. Silverman | 1,700,600 | $14,200 | 4.54% | |
| 2. | Prescott Group Capital Management Phil Frohlich | 2,133,568 | $17,815 | +5% | 3.69% |
| 3. | Casdin Capital Eli Casdin | 1,600,000 | $13,360 | +9% | 3.25% |
| 4. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 6,679,954 | $55,778 | +3% | 2.47% |
| 5. | Springbok Capital Gavin Saitowitz And Cisco J. Del Valle | 48,891 | $408 | 0.03% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.98 | 10,000 | Director | 348,234 | 2015-08-21 | Filing | |
| $4.83 | 10,000 | Director | 320,340 | 2016-11-15 | Filing | |
| $3.47 | 10,000 | Director | 290,246 | 2015-09-11 | Filing | |
| $3.84 | 10,000 | Director | 280,246 | 2015-08-24 | Filing | |
| $3.97 | 20,000 | Director | 270,246 | 2015-08-14 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $10.37 | 6,000 | Director | 56,679 | 2018-04-03 | Filing | |
| $11.06 | 12,500 | Director | 172,170 | 2018-03-29 | Filing | |
| $11.05 | 12,500 | Director | 184,670 | 2018-03-28 | Filing | |
| $11.14 | 12,500 | Director | 116,254 | 2018-03-27 | Filing | |
| $11.15 | 29,166 | Director | 128,754 | 2018-03-26 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 59,325 | $653 | 0.57% | |
| 2. | 27,000 | $297 | 0.26% | |
| 3. | 79,934 | $879 | 0.25% | |
| 4. | 8,516 | $94 | 0.01% | |
| 5. | 60,200 | $662 | 0% |
