| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Broadfin Capital Kevin Kotler | 6,772,764 | $21,131 | -1% | 3.32% |
| 2. | Consonance Capital Management Mitchell Blutt | 6,044,719 | $18,860 | +22% | 1.21% |
| 3. | Dorset Management David M. Knott | 513,475 | $1,602 | +6% | 0.6% |
| 4. | VenBio Select Advisor Kurt Von Emster | 4,497,042 | $14,031 | -5% | 0.54% |
| 5. | Pura Vida Investments Efrem Kamen | 150,000 | $468 | 0.39% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.41 | 20,000 | Director | 140,000 | 2018-06-08 | Filing | |
| $3.35 | 1,000 | Director | 523,376 | 2018-06-07 | Filing | |
| $3.31 | 4,000 | Director | 522,376 | 2018-06-07 | Filing | |
| $3.74 | 5,000 | Director | 518,376 | 2018-06-01 | Filing | |
| $3.75 | 20,000 | Director | 120,000 | 2018-05-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.34 | 22,800 | Officer | 74,131 | 2015-10-23 | Filing | |
| $1.25 | 216,546 | Director | 87,636 | 2011-09-06 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 250,683 | $782 | 1.87% | |
| 2. | 445,264 | $1,506 | 1.22% | |
| 3. | 488,243 | $1,523 | 0.16% | |
| 4. | 161,089 | $503 | 0.07% | |
| 5. | 1,053,871 | $3,288 | 0.06% |
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