| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Darwin Global Management Abhishek Trehan | 3,057,412 | $456,104,722 | +1% | 12.1% |
| 2. | Paradigm Biocapital Advisors Senai Asefaw | 1,114,784 | $177,741,161 | 3.63% | |
| 3. | Millennium Management Israel Englander | 570,088 | $90,894,831 | +3% | 0.04% |
| 4. | Holocene Advisors Brandon Haley | 494,495 | $78,842,283 | +489% | 0.19% |
| 5. | Deerfield Management James E. Flynn | 304,013 | $48,471,833 | +31% | 0.57% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $155.25 | 9 | $1,397.28 | 0 | 2026-05-07 | Filing | |
| $154.61 | 3 | $463.83 | 9 | 2026-05-07 | Filing | |
| $153.56 | 428 | $65,725.18 | 12 | 2026-05-07 | Filing | |
| $152.45 | 226 | $34,453.09 | 440 | 2026-05-07 | Filing | |
| $156.00 | 100 | $15,600.00 | 666 | 2026-05-06 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 768,359 | $122,507,159 | 0.02% | |
| 2. | 715,332 | $114,052,534 | 1.13% | |
| 3. | 357,650 | $57,023,716 | 0.94% | |
| 4. | 201,409 | $32,112,649 | 0% | |
| 5. | 116,684 | $18,604,097 | 3.3% |
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