| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Darwin Global Management Abhishek Trehan | 3,077,219 | $456,588,244 | +1% | 12.14% |
| 2. | Paradigm Biocapital Advisors Senai Asefaw | 1,232,877 | $189,844,565 | +11% | 3.55% |
| 3. | Millennium Management Israel Englander | 494,564 | $76,155,438 | -14% | 0.03% |
| 4. | Maverick Capital Lee Ainslie | 396,311 | $61,025,949 | 0.54% | |
| 5. | Deerfield Management James E. Flynn | 357,199 | $55,003,288 | +18% | 0.57% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $180.57 | 223 | $40,267.11 | 93,433 | 2026-08-12 | Filing | |
| $180.00 | 144 | $25,920.00 | 93,656 | 2026-08-12 | Filing | |
| $180.57 | 223 | $40,267.11 | 170,569 | 2026-08-12 | Filing | |
| $180.00 | 142 | $25,560.00 | 170,792 | 2026-08-12 | Filing | |
| $147.11 | 96 | $14,122.56 | 15,000 | 2026-06-18 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 715,332 | $110,150,398 | 0.94% | |
| 2. | 390,829 | $60,181,804 | 0.8% | |
| 3. | 235,071 | $36,197,407 | 0% | |
| 4. | 224,989 | $34,644,931 | 0% | |
| 5. | 166,188 | $25,590,459 | 0% |
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