| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Darwin Global Management Abhishek Trehan | 3,027,704 | $486,915,357 | 9.86% | |
| 2. | Millennium Management Israel Englander | 558,882 | $89,398,765 | +2595% | 0.04% |
| 3. | RA Capital Management Peter Kolchinsky | 432,484 | $69,180,141 | -51% | 0.71% |
| 4. | Perceptive Advisors Joseph Edelman | 414,239 | $66,261,670 | +733% | 1.18% |
| 5. | Point72 Asset Management Steve Cohen | 284,437 | $45,498,543 | +9076% | 0.05% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $158.19 | 22 | $3,480.27 | 5,666 | 2026-04-29 | Filing | |
| $157.39 | 102 | $16,053.36 | 5,688 | 2026-04-29 | Filing | |
| $156.43 | 339 | $53,029.91 | 5,790 | 2026-04-29 | Filing | |
| $155.52 | 259 | $40,280.41 | 6,129 | 2026-04-29 | Filing | |
| $154.58 | 278 | $42,972.68 | 6,388 | 2026-04-29 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 4,187 | $667,575 | 0.28% | |
| 2. | 3,500 | $558,040 | 0.13% | |
| 3. | 1,707 | $272,164 | 0.01% | |
| 4. | 1,415 | $225,608 | 0% | |
| 5. | 83 | $13,234 | 0.01% |
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