| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Third Point Dan Loeb | 36,000,000 | $2,341,440 | 17.58% | |
| 2. | Healthcor Management LP Arthur B Cohen And Joseph Healey | 2,124,670 | $138,189 | +24% | 4.69% |
| 3. | Pura Vida Investments Efrem Kamen | 75,000 | $4,878,000 | +8% | 4.08% |
| 4. | 13D Management Kenneth Squire | 200,318 | $13,029 | -12% | 3.61% |
| 5. | Sivik Global Healthcare Krishen Sud | 100,000 | $6,504 | 3.03% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $42.75 | 11,691 | Officer, Director | 11,691 | 2016-05-23 | Filing | |
| $72.38 | 50 | Director | 696 | 2014-04-24 | Filing | |
| $68.00 | 55 | Director | 646 | 2014-03-25 | Filing | |
| $67.39 | 81 | Director | 591 | 2014-03-20 | Filing | |
| $68.54 | 96 | Director | 510 | 2014-02-27 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $71.96 | 25,000 | Officer | 65,115 | 2018-05-22 | Filing | |
| $72.00 | 31,395 | Officer | 97,382 | 2018-05-21 | Filing | |
| $71.79 | 6,594 | Director | 9,848 | 2018-05-22 | Filing | |
| $70.57 | 20,000 | Officer | 65,115 | 2018-05-15 | Filing | |
| $69.61 | 36,359 | Officer | 65,115 | 2018-05-08 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 715,438 | $46,532 | 8.38% | |
| 2. | 9,544,502 | $620,774 | 5.02% | |
| 3. | 78,598 | $5,112 | 4.56% | |
| 4. | 80,687 | $5,248 | 3.51% | |
| 5. | 565,891 | $36,806 | 3.21% |
