| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Tamarack Capital Management Justin John Ferayorni | 600,000 | $20,154 | -31% | 7.63% |
| 2. | DAFNA Capital Management Nathan Fischel | 239,729 | $8,052 | -25% | 3.36% |
| 3. | Pura Vida Investments Efrem Kamen | 388,994 | $13,066 | 3.32% | |
| 4. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 256,606 | $8,619 | -52% | 1.65% |
| 5. | OrbiMed Advisors Samuel Isaly | 928,189 | $31,178 | +451% | 0.52% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $24.86 | 500 | Director | 25,670 | 2019-09-12 | Filing | |
| $17.64 | 11,000 | Director | 16,805 | 2018-03-01 | Filing | |
| $17.43 | 1,000 | Director | 10,469 | 2018-03-01 | Filing | |
| $18.36 | 1,500 | Director | 10,969 | 2017-11-08 | Filing | |
| $15.05 | 500 | Officer | 3,500 | 2014-05-06 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $47.00 | 25,000 | Officer, Director | 514,147 | 2020-05-12 | Filing | |
| $46.00 | 25,000 | Officer, Director | 514,147 | 2020-05-11 | Filing | |
| $45.00 | 25,000 | Officer, Director | 514,147 | 2020-05-08 | Filing | |
| $40.00 | 10,000 | Officer | 51,255 | 2020-04-17 | Filing | |
| $36.07 | 4,000 | Director | 73,106 | 2020-04-07 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 750,818 | $25,220 | 4.3% | |
| 2. | 126,363 | $4,245 | 2.84% | |
| 3. | 50,750 | $1,705 | 2.05% | |
| 4. | 28,814 | $968 | 1.46% | |
| 5. | 51,371 | $1,726 | 1% |
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