| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 1,228,189 | $68,373 | 0.59% | |
| 2. | Pura Vida Investments Efrem Kamen | 715,649 | $39,840 | +11% | 1.44% |
| 3. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 644,217 | $35,864 | -10% | 2.52% |
| 4. | Tamarack Capital Management Justin John Ferayorni | 366,400 | $19,632 | +5% | 4.09% |
| 5. | Citadel Investment Group Ken Griffin | 266,463 | $14,834 | -4% | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $40.54 | 12,350 | Director | 41,036 | 2020-11-17 | Filing | |
| $24.86 | 500 | Director | 25,670 | 2019-09-12 | Filing | |
| $17.64 | 11,000 | Director | 16,805 | 2018-03-01 | Filing | |
| $17.43 | 1,000 | Director | 10,469 | 2018-03-01 | Filing | |
| $18.36 | 1,500 | Director | 10,969 | 2017-11-08 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $65.28 | 3,000 | Director | 72,558 | 2021-04-01 | Filing | |
| $29.25 | 3,500 | Officer | 0 | 2019-03-06 | Filing | |
| $29.25 | 7,500 | Officer | 88,439 | 2019-03-06 | Filing | |
| $65.00 | 25,000 | Officer, Director | 504,795 | 2021-02-12 | Filing | |
| $64.00 | 25,000 | Officer, Director | 504,795 | 2021-02-11 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 924,413 | $60,568 | 0.55% | |
| 2. | 539,856 | $35,371 | 1.17% | |
| 3. | 501,311 | $32,846 | 1.18% | |
| 4. | 462,113 | $30,278 | 0.12% | |
| 5. | 87,200 | $5,713 | 0.3% |
