| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 3,672,872 | $311,937 | 4.36% | |
| 2. | Marshall Wace LLP Paul Marshall And Ian Wace | 863,107 | $73,304 | +798% | 0.4% |
| 3. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 746,000 | $63,358 | +55% | 1.34% |
| 4. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 532,125 | $45,193 | -25% | 3.18% |
| 5. | Point72 Asset Management Steve Cohen | 500,000 | $42,465 | +690% | 0.2% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $70.00 | 142,857 | Director | 822,857 | 2020-12-18 | Filing | |
| $23.99 | 8,333 | Director | 42,718 | 2020-11-09 | Filing | |
| $30.26 | 2,000 | Director | 79,546 | 2020-06-17 | Filing | |
| $32.30 | 3,000 | Director | 77,546 | 2020-06-02 | Filing | |
| $38.18 | 2,500 | Director | 29,520 | 2020-03-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $77.45 | 894 | Officer | 78,645 | 2021-03-02 | Filing | |
| $77.45 | 2,221 | Officer | 158,249 | 2021-03-02 | Filing | |
| $77.45 | 8,115 | Officer, Director | 827,643 | 2021-03-02 | Filing | |
| $80.25 | 600 | Officer, Director | 816,200 | 2021-02-16 | Filing | |
| $79.72 | 13,223 | Officer, Director | 816,800 | 2021-02-16 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 23,988 | $2,037,301 | 0% | |
| 2. | 6,610 | $561,387 | 0% | |
| 3. | 5,090,038 | $432,297 | 0.03% | |
| 4. | 3,589,554 | $304,861 | 74.36% | |
| 5. | 2,815,747 | $239,142 | 0% |
