| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | 12 West Capital Management Joel Ramin | 735,000 | $53,589 | 5.51% | |
| 2. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 495,341 | $36,115 | +29% | 4.9% |
| 3. | Casdin Capital Eli Casdin | 355,000 | $25,883 | +32% | 4.42% |
| 4. | Sio Capital Michael Castor | 154,637 | $11,275 | +49% | 4.1% |
| 5. | Bridger Management Roberto Mignone | 658,785 | $48,032 | -9% | 4% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $71.87 | 297,501 | Large Shareholder | 10,554,134 | 2017-05-31 | Filing | |
| $65.35 | 11,500 | Officer | 11,500 | 2017-05-30 | Filing | |
| $37.00 | 27,900 | Director | 27,900 | 2016-10-13 | Filing | |
| $58.36 | 2,000 | Director | 4,000 | 2016-03-09 | Filing | |
| $69.75 | 205,030 | Large Shareholder | 10,256,633 | 2016-02-01 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $120.00 | 2,500 | Officer | 1,916 | 2018-08-30 | Filing | |
| $106.25 | 1,400 | Officer, Director | 151,297 | 2018-07-25 | Filing | |
| $105.83 | 34,995 | Officer, Director | 152,697 | 2018-07-25 | Filing | |
| $104.83 | 7,758 | Officer, Director | 187,692 | 2018-07-25 | Filing | |
| $103.69 | 3,847 | Officer, Director | 195,450 | 2018-07-25 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 1,571,389 | $114,570 | 3.67% | |
| 2. | 439,498 | $32,044 | 2.94% | |
| 3. | 31,959 | $2,330 | 1.83% | |
| 4. | 500,000 | $36,455 | 1.35% | |
| 5. | 33,800 | $1,935 | 1.2% |
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