| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 3,618,748 | $38,124 | -13% | 0.69% |
| 2. | OrbiMed Advisors Samuel Isaly | 2,725,313 | $28,711 | -55% | 0.36% |
| 3. | Casdin Capital Eli Casdin | 1,650,000 | $17,383 | +54% | 0.77% |
| 4. | Deerfield Management James E. Flynn | 1,461,978 | $15,402 | -13% | 0.37% |
| 5. | Two Sigma Advisors John Overdeck And David Siegel | 498,500 | $5,252 | +1562% | 0.01% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $25.00 | 20,000 | Director | 44,621 | 2020-02-03 | Filing | |
| $19.00 | 203,200 | Large Shareholder, Director | 203,200 | 2019-02-11 | Filing | |
| $19.00 | 50,561 | Large Shareholder, Director | 2,455,853 | 2019-02-11 | Filing | |
| $19.00 | 157,939 | Large Shareholder, Director | 10,434,976 | 2019-02-11 | Filing | |
| $19.00 | 203,200 | Large Shareholder, Director | 203,200 | 2019-02-11 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $23.58 | 378 | Officer | 213,719 | 2020-07-15 | Filing | |
| $22.94 | 9,622 | Officer | 214,097 | 2020-07-15 | Filing | |
| $31.54 | 4,377 | Large Shareholder, Director | 12,853,817 | 2020-06-23 | Filing | |
| $31.54 | 4,377 | Large Shareholder | 12,853,817 | 2020-06-23 | Filing | |
| $29.90 | 3,909 | Officer | 223,719 | 2020-06-15 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 40,747 | $429,269 | 0% | |
| 2. | 29,470 | $310,466 | 0% | |
| 3. | 5,900 | $62,153 | 0.01% | |
| 4. | 5,345,271 | $56,311 | 0% | |
| 5. | 4,882,002 | $51,432 | 0% |
