| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Alkeon Capital Management Panayotis Takis Sparaggis | 3,220,730 | $123,225,130 | -1% | 0.27% |
| 2. | Avidity Partners Management David Witzke And Michael Gregory | 2,447,000 | $93,622,220 | -37% | 3.1% |
| 3. | Adage Capital Management Phill Gross And Robert Atchinson | 2,389,891 | $91,437,230 | +81% | 0.2% |
| 4. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,368,378 | $90,614,142 | 0.49% | |
| 5. | Redmile Group Jeremy Green | 2,044,389 | $78,218,323 | -23% | 3.39% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $42.00 | 120,000 | 520,000 | 2023-05-19 | Filing | ||
| $26.00 | 400,000 | 400,000 | 2023-09-19 | Filing | ||
| $36.00 | 415,000 | Large Shareholder | 5,830,203 | 2020-07-10 | Filing | |
| $36.00 | 415,000 | Large Shareholder, Director | 5,830,203 | 2020-07-10 | Filing | |
| $16.00 | 270,000 | Director | 505,099 | 2019-06-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $45.50 | 3,477 | Officer, Director | 409,293 | 2023-05-01 | Filing | |
| $45.00 | 21,523 | Officer, Director | 412,770 | 2023-05-01 | Filing | |
| $38.83 | 1,708 | Officer, Director | 369,293 | 2023-04-03 | Filing | |
| $37.88 | 23,292 | Officer, Director | 371,001 | 2023-04-03 | Filing | |
| $47.17 | 6,700 | Officer, Director | 370,999 | 2023-03-01 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,811,676 | $145,826,409 | 0.09% | |
| 2. | 3,271,829 | $125,180,178 | 50.58% | |
| 3. | 2,783,377 | $106,492,004 | 0% | |
| 4. | 2,230,807 | $85,350,676 | 0% | |
| 5. | 2,138,893 | $81,834,046 | 0% |
