| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 4,319,496 | $383,484,855 | +15% | 5.76% |
| 2. | Paradigm Biocapital Advisors Senai Asefaw | 3,840,778 | $340,984,271 | +97% | 6.38% |
| 3. | Driehaus Capital Richard Driehaus | 2,799,166 | $248,509,957 | +1% | 1.44% |
| 4. | Tang Capital Management Kevin C. Tang | 1,892,200 | $167,989,516 | 7.63% | |
| 5. | Adage Capital Management Phill Gross And Robert Atchinson | 1,722,300 | $152,905,794 | 0.21% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $0.56 | 90,000 | $50,472.00 | 90,000 | 2022-08-25 | Filing | |
| $0.71 | 28,200 | $20,022.00 | 36,200 | 2022-06-08 | Filing | |
| $2.34 | 80,079 | $187,705.18 | 550,540 | 2022-03-16 | Filing | |
| $1.86 | 42,417 | $78,942.28 | 473,461 | 2022-03-15 | Filing | |
| $1.93 | 67,472 | $130,220.96 | 431,044 | 2022-03-14 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $93.46 | 2,600 | $242,996.00 | 2,845 | 2026-10-01 | Filing | |
| $92.70 | 2,100 | $194,670.00 | 5,445 | 2026-10-01 | Filing | |
| $91.35 | 7,228 | $660,277.80 | 7,545 | 2026-10-01 | Filing | |
| $90.35 | 16,605 | $1,500,261.75 | 14,773 | 2026-10-01 | Filing | |
| $89.24 | 400 | $35,696.00 | 31,378 | 2026-10-01 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 13,026,187 | $1,156,464,882 | 0.05% | |
| 2. | 6,506,605 | $577,656,391 | 0.01% | |
| 3. | 4,251,996 | $377,492,205 | 3.22% | |
| 4. | 3,448,681 | $306,173,899 | 0.01% | |
| 5. | 3,057,416 | $271,437,392 | 0.01% |
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