| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Knoll Capital Management Fred Knoll | 2,359,767 | $29,639 | 25.05% | |
| 2. | Nexthera Capital Ori Hershkovitz | 849,979 | $10,880 | +36% | 2.08% |
| 3. | Cormorant Asset Management Bihua Chen | 500,000 | $6,400 | -9% | 0.41% |
| 4. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,184,364 | $27,960 | 0.18% | |
| 5. | Perceptive Advisors Joseph Edelman | 659,636 | $5,145 | -48% | 0.13% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $5.48 | 5,000 | Director | 75,000 | 2016-09-20 | Filing | |
| $5.50 | 20,000 | Director | 70,000 | 2015-07-31 | Filing | |
| $5.50 | 18,182 | Director | 343,182 | 2015-07-31 | Filing | |
| $4.00 | 25,000 | Director | 25,000 | 2015-01-26 | Filing | |
| $4.00 | 250,000 | Large Shareholder, Director | 315,042 | 2014-12-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $0.55 | 179,157 | Large Shareholder | 2,413,163 | 2012-06-29 | Filing | |
| $0.68 | 25,000 | Large Shareholder | 2,592,320 | 2012-06-28 | Filing | |
| $0.85 | 1,000 | Large Shareholder | 2,757,620 | 2012-05-15 | Filing | |
| $0.67 | 140,300 | Large Shareholder | 2,617,320 | 2012-05-16 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 20,177 | $258 | 1.32% | |
| 2. | 336,939 | $4,313 | 0.49% | |
| 3. | 32,301 | $413 | 0.14% | |
| 4. | 26,455 | $339 | 0.11% | |
| 5. | 12,530 | $160 | 0.1% |
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