13D Filing: RA Capital Management and Biocryst Pharmaceuticals Inc (BCRX)

Page 2 of 8 – SEC Filing

1 NAME OF REPORTING PERSON
RA Capital Management, LLC
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐
(b) ☐
3 SEC USE ONLY
4 SOURCE OF FUNDS
AF
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e)     ☐
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Massachusetts
NUMBER OF 7 SOLE VOTING POWER
SHARES
BENEFICIALLY – 0 –
OWNED BY 8 SHARED VOTING POWER
EACH
REPORTING 6,984,692
PERSON WITH 9 SOLE DISPOSITIVE POWER
– 0 –
10 SHARED DISPOSITIVE POWER
6,984,692
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
6,984,692
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES     ☐
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
7.1%*
14 TYPE OF REPORTING PERSON
IA, OO (Limited Liability Company)

* The aggregate percentage
of Shares reported owned by each Reporting Person is based upon 98,606,110 Shares outstanding, which is the total number of Shares
outstanding as of January 31, 2018, as reported in the Issuer’s Annual Report on Form 10-K/A, filed with the Securities and
Exchange Commission on March 27, 2018.

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