| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 2,590,303 | $99,830,278 | 4.05% | |
| 2. | Opaleye Management James A. Silverman | 255,087 | $9,831,053 | 1.39% | |
| 3. | Woodline Partners Michael Rockefeller And Karl Kroeker | 209,945 | $8,091,280 | +17% | 0.04% |
| 4. | Stonepine Capital Timothy P. Lynch | 115,459 | $4,449,790 | -25% | 3.62% |
| 5. | HighVista Strategies Andre F. Perold | 105,714 | $4,074,218 | -8% | 1% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $25.39 | 2,000 | $50,780.00 | 7,045 | 2025-06-30 | Filing | |
| $24.70 | 2,000 | $49,400.00 | 5,045 | 2025-04-07 | Filing | |
| $25.60 | 5,243 | $134,220.80 | 10,000 | 2025-04-07 | Filing | |
| $25.56 | 3,346 | $85,523.76 | 4,757 | 2025-04-04 | Filing | |
| $25.25 | 3,476 | $87,769.00 | 20,000 | 2025-04-04 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $36.81 | 15 | $552.15 | 30,079 | 2025-09-22 | Filing | |
| $36.93 | 15 | $553.95 | 30,094 | 2025-09-22 | Filing | |
| $35.98 | 4,300 | $154,714.00 | 30,109 | 2025-09-22 | Filing | |
| $25.38 | 25,637 | $650,667.06 | 62,701 | 2025-05-20 | Filing | |
| $25.38 | 10,482 | $266,033.16 | 22,563 | 2025-05-20 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 1,646,996 | $63,475,232 | 0% | |
| 2. | 1,074,325 | $41,404,491 | 0% | |
| 3. | 668,111 | $25,748,997 | 0% | |
| 4. | 592,902 | $22,850,443 | 0% | |
| 5. | 211,977 | $8,171,434 | 0% |