| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Sio Capital Michael Castor | 852,160 | $8,470 | +34% | 2.28% |
| 2. | Opaleye Management James A. Silverman | 485,000 | $4,821 | -42% | 1.33% |
| 3. | Dorset Management David M. Knott | 218,102 | $2,168 | -9% | 0.86% |
| 4. | DAFNA Capital Management Nathan Fischel | 179,200 | $1,781 | 0.76% | |
| 5. | Rubric Capital Management David Rosen | 810,000 | $8,051 | 0.75% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $9.82 | 9,500 | Director | 9,500 | 2018-05-31 | Filing | |
| $5.16 | 30,000 | Director | 30,000 | 2018-05-29 | Filing | |
| $5.21 | 8,000 | Director | 8,000 | 2018-05-29 | Filing | |
| $5.22 | 47,965 | Director | 47,965 | 2018-05-29 | Filing | |
| $1.21 | 13,000 | Director | 39,250 | 2016-11-15 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $19.15 | 262,881 | Large Shareholder | 6,038,083 | 2018-09-25 | Filing | |
| $9.25 | 21,551 | Officer | 94,035 | 2018-05-31 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 250,000 | $2,485 | 9.57% | |
| 2. | 100,000 | $994 | 3.82% | |
| 3. | 150,000 | $1,491 | 1.79% | |
| 4. | 118,549 | $1,178 | 0.64% | |
| 5. | 28,854 | $287 | 0.61% |
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