| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 1,750,000 | $64,453 | +17% | 0.91% |
| 2. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 1,583,358 | $58,315 | +1% | 1.78% |
| 3. | Marshall Wace LLP Paul Marshall And Ian Wace | 1,537,905 | $56,641 | +466% | 0.37% |
| 4. | Redmile Group Jeremy Green | 1,128,827 | $41,575 | -10% | 0.76% |
| 5. | 1,062,500 | $39,132 | 1.19% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $44.71 | 600 | Officer, Director | 273,467 | 2020-11-18 | Filing | |
| $43.98 | 5,776 | Officer, Director | 274,067 | 2020-11-18 | Filing | |
| $43.11 | 3,937 | Officer, Director | 279,843 | 2020-11-18 | Filing | |
| $36.49 | 300 | Officer, Director | 280,564 | 2020-10-14 | Filing | |
| $35.82 | 4,950 | Officer, Director | 280,864 | 2020-10-14 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 599,298 | $22,072,145 | 0.01% | |
| 2. | 14,499 | $533,998 | 0% | |
| 3. | 5,272 | $194,168 | 0% | |
| 4. | 4,059,794 | $149,522 | 0.01% | |
| 5. | 3,378,207 | $124,419 | 0.29% |
