| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 12,198,625 | $389,624,083 | 3.39% | |
| 2. | Commodore Capital Egen Atkinson And Michael Kramarz | 1,875,000 | $59,887,500 | -25% | 3.57% |
| 3. | Paradigm Biocapital Advisors Senai Asefaw | 1,828,607 | $58,405,708 | -12% | 1.09% |
| 4. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,476,196 | $47,149,700 | -26% | 1.21% |
| 5. | Deerfield Management James E. Flynn | 1,017,000 | $32,482,980 | +86% | 0.34% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.58 | 972 | $20,000.03 | 972 | 2026-09-09 | Filing | |
| $10.13 | 11,813 | $119,665.69 | 10,259,291 | 2025-06-16 | Filing | |
| $10.20 | 120,167 | $1,225,703.40 | 10,247,478 | 2025-06-13 | Filing | |
| $10.20 | 31,307 | $319,331.40 | 10,127,311 | 2025-06-12 | Filing | |
| $10.19 | 186,850 | $1,904,001.50 | 10,096,004 | 2025-06-09 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $36.97 | 14,295 | $528,506.16 | 28,231 | 2026-03-25 | Filing | |
| $33.37 | 5,872 | $195,928.68 | 146,981 | 2026-02-12 | Filing | |
| $31.50 | 2,128 | $67,035.83 | 152,853 | 2026-02-12 | Filing | |
| $29.08 | 1,017 | $29,575.17 | 154,981 | 2026-01-12 | Filing | |
| $28.44 | 6,983 | $198,610.49 | 155,998 | 2026-01-12 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 8,920,513 | $284,921,184 | 0.01% | |
| 2. | 4,352,448 | $139,161,460 | 0.06% | |
| 3. | 3,823,425 | $122,120,195 | 95.92% | |
| 4. | 3,553,585 | $113,501,505 | 5.39% | |
| 5. | 3,248,980 | $103,772,421 | 2.49% |
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