| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 2,149,057 | $20,180 | 0.79% | |
| 2. | Frazier Healthcare Partners Alan Frazier | 841,908 | $7,906 | 0.6% | |
| 3. | Kingdon Capital Mark Kingdon | 761,495 | $7,150 | +60% | 0.77% |
| 4. | Endurant Capital Management Vishal Saluja And Pham Quang | 681,243 | $6,397 | +62% | 2.3% |
| 5. | Woodline PartnersKarl Michael Rockefeller And Kroeker | 517,670 | $4,861 | -54% | 0.12% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $11.48 | 75,000 | Large Shareholder | 8,036,105 | 2021-02-24 | Filing | |
| $11.29 | 235,004 | Large Shareholder | 7,961,105 | 2021-02-23 | Filing | |
| $12.65 | 1,185,770 | Large Shareholder | 7,726,101 | 2021-02-18 | Filing | |
| $11.69 | 80,000 | Large Shareholder | 6,540,331 | 2021-02-01 | Filing | |
| $11.94 | 80,000 | Large Shareholder | 6,460,331 | 2021-01-29 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $13.05 | 500,000 | Large Shareholder, Director | 6,097,298 | 2020-09-16 | Filing | |
| $13.05 | 500,000 | Large Shareholder | 6,097,298 | 2020-09-16 | Filing | |
| $10.75 | 1,049 | Large Shareholder | 0 | 2020-08-28 | Filing | |
| $10.75 | 2,447 | Large Shareholder | 0 | 2020-08-28 | Filing | |
| $16.51 | 300,000 | Large Shareholder, Director | 6,597,298 | 2020-05-20 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 22,300 | $209,397 | 0% | |
| 2. | 6,412,331 | $60,211 | 0.68% | |
| 3. | 4,988 | $46,837 | 0% | |
| 4. | 3,078,709 | $28,909 | 0% | |
| 5. | 2,378,404 | $22,332 | 0% |
