| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 6,995,858 | $73,946,219 | 1.25% | |
| 2. | Driehaus Capital Richard Driehaus | 4,680,431 | $49,472,156 | +50% | 0.4% |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 4,396,124 | $46,467,031 | 1.66% | |
| 4. | Samsara BioCapital Srini Akkaraju And Michael Dybbs | 3,149,128 | $33,286,283 | 6.81% | |
| 5. | Siren L.L.C. Raymond Debbane | 2,202,514 | $23,280,573 | 1.2% |