| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 6,995,858 | $131,592,089 | 1.62% | |
| 2. | Driehaus Capital Richard Driehaus | 4,919,896 | $92,543,244 | +6% | 0.66% |
| 3. | Biotechnology Value Fund / BVF Inc Mark Lampert | 4,015,790 | $75,537,010 | -9% | 3.06% |
| 4. | Samsara BioCapital Srini Akkaraju And Michael Dybbs | 3,149,128 | $59,235,098 | 7.73% | |
| 5. | Siren L.L.C. Raymond Debbane | 2,202,514 | $41,429,288 | 1.62% |