| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 2,035,986 | $681,627,753 | 10.23% | |
| 2. | Baker Bros. Advisors Julian Baker And Felix Baker | 1,753,198 | $586,953,158 | 2.94% | |
| 3. | Orbis Investment Management William B. Gray | 1,529,788 | $512,157,724 | -39% | 1.76% |
| 4. | Adage Capital Management Phill Gross And Robert Atchinson | 1,015,480 | $339,972,549 | +25% | 0.48% |
| 5. | Deerfield Management James E. Flynn | 963,351 | $322,520,281 | 3.36% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $1.75 | 14,500 | $25,375.00 | 14,500 | 2023-10-05 | Filing | |
| $1.06 | 10,000 | $10,587.00 | 45,002 | 2023-06-27 | Filing | |
| $0.87 | 8,000 | $6,997.60 | 46,416 | 2023-03-24 | Filing | |
| $0.86 | 35,002 | $30,206.51 | 35,002 | 2023-03-23 | Filing | |
| $0.86 | 35,000 | $30,159.50 | 226,299 | 2023-03-23 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $315.71 | 837 | $264,245.09 | 2,337 | 2026-06-24 | Filing | |
| $314.90 | 1,279 | $402,758.38 | 3,174 | 2026-06-24 | Filing | |
| $313.66 | 504 | $158,086.15 | 4,453 | 2026-06-24 | Filing | |
| $312.83 | 1,004 | $314,081.32 | 4,957 | 2026-06-24 | Filing | |
| $311.91 | 2,854 | $890,202.56 | 5,961 | 2026-06-24 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 3,421,374 | $1,145,994,051 | 0.47% | |
| 2. | 2,316,907 | $775,677,279 | 0.03% | |
| 3. | 2,292,585 | $767,534,532 | 0.01% | |
| 4. | 1,335,185 | $447,006,586 | 0.02% | |
| 5. | 1,235,299 | $413,565,752 | 0.01% |
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