| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,141,701 | $1,247,198,160 | 7.3% | |
| 2. | VenBio Select Advisor Kurt Von Emster | 1,807,500 | $1,052,579,550 | -2% | 10.35% |
| 3. | Paulson & Co John Paulson | 1,707,522 | $994,358,361 | -11% | 30.48% |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 270,151 | $157,319,733 | +2% | 0.61% |
| 5. | Armistice Capital Steven Boyd | 265,705 | $154,730,650 | +122% | 1.84% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $392.24 | 9,362 | $3,672,178.03 | 1,947,968 | 2025-08-20 | Filing | |
| $392.24 | 862 | $338,113.38 | 202,813 | 2025-08-20 | Filing | |
| $389.89 | 2,506 | $977,058.83 | 1,938,606 | 2025-08-20 | Filing | |
| $389.89 | 231 | $90,064.08 | 201,951 | 2025-08-20 | Filing | |
| $389.00 | 366 | $142,374.00 | 1,936,100 | 2025-08-20 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $437.65 | 40 | $17,506.00 | 12,490 | 2026-03-06 | Filing | |
| $436.69 | 80 | $34,935.20 | 12,530 | 2026-03-06 | Filing | |
| $435.32 | 80 | $34,825.20 | 12,610 | 2026-03-06 | Filing | |
| $434.20 | 160 | $69,472.00 | 12,690 | 2026-03-06 | Filing | |
| $432.56 | 116 | $50,176.48 | 12,850 | 2026-03-06 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 396 | $207,294 | 0.01% | |
| 2. | 277 | $145,001 | 0% | |
| 3. | 127 | $66,481 | 0% | |
| 4. | 127 | $66,481 | 0% | |
| 5. | 109 | $57,753 | 0% |
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