| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 4,375,217 | $100,017 | 1.39% | |
| 2. | Consonance Capital Management Mitchell Blutt | 2,299,829 | $52,574 | -39% | 4.91% |
| 3. | Citadel Investment Group Ken Griffin | 1,641,261 | $37,520 | +187% | 0.01% |
| 4. | Point72 Asset Management Steve Cohen | 1,460,133 | $33,379 | -60% | 0.16% |
| 5. | Perceptive Advisors Joseph Edelman | 1,261,060 | $28,828 | -3% | 0.3% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $17.20 | 10,000 | Director | 59,435 | 2016-03-03 | Filing | |
| $16.00 | 46,875 | Director | 46,875 | 2013-10-16 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $30.91 | 5,000 | Officer | 0 | 2021-04-15 | Filing | |
| $33.00 | 15,000 | Officer | 143,460 | 2021-03-22 | Filing | |
| $32.00 | 3,917 | Officer | 79,890 | 2021-03-22 | Filing | |
| $26.50 | 21,749 | Officer | 0 | 2021-03-08 | Filing | |
| $24.10 | 500 | Officer | 44,468 | 2020-12-29 | Filing |
