| No. | Hedge Fund | Shares | Value | Activity | % Port | 
|---|---|---|---|---|---|
| 1. | Caligan Partners David Johnson | 8,118,892 | $101,161,394 | +1% | 19.45% | 
| 2. | Farallon Capital Thomas Steyer | 4,238,762 | $52,814,975 | +7% | 0.23% | 
| 3. | Findell Capital Management Brian Finn | 3,000,000 | $37,380,000 | +4% | 18.2% | 
| 4. | Opaleye Management James A. Silverman | 2,475,000 | $30,838,500 | +10% | 6.24% | 
| 5. | Deerfield Management James E. Flynn | 1,616,778 | $20,145,054 | 0.37% | 
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 | 
|---|---|---|---|---|---|---|
| $8.90 | 337,078 | $2,999,994.20 | 816,311 | 2024-09-12 | Filing | |
| $9.51 | 150,000 | $1,426,500.00 | 6,994,997 | 2024-08-30 | Filing | |
| $7.16 | 139,665 | $1,000,001.40 | 640,805 | 2023-12-14 | Filing | |
| $7.16 | 279,330 | $2,000,002.80 | 279,330 | 2023-12-14 | Filing | |
| $7.16 | 1,117,318 | $7,999,996.88 | 11,280,945 | 2023-12-14 | Filing | 
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 | 
|---|---|---|---|---|---|---|
| $22.93 | 692 | $15,867.56 | 174,998 | 2025-10-27 | Filing | |
| $22.93 | 1,073 | $24,603.89 | 184,338 | 2025-10-27 | Filing | |
| $23.41 | 7,839 | $183,510.99 | 576,017 | 2025-10-13 | Filing | |
| $23.41 | 11,630 | $272,258.30 | 352,646 | 2025-10-13 | Filing | |
| $23.41 | 4,900 | $114,709.00 | 153,462 | 2025-10-13 | Filing | 
| No. | Name | Shares | Value | % Port | 
|---|---|---|---|---|
| 1. | 89,086 | $2,025,816 | 0.15% | |
| 2. | 64,600 | $1,472,880 | 0.02% | |
| 3. | 28,385 | $645,475 | 0.17% | |
| 4. | 25,760 | $585,782 | 0% | |
| 5. | 18,641 | $423,896 | 0.01% |