| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Darwin Global Management Abhishek Trehan | 20,933,277 | $3,644,274,193 | +3% | 73.78% |
| 2. | Baker Bros. Advisors Julian Baker And Felix Baker | 6,592,746 | $1,147,401,514 | -2% | 6.72% |
| 3. | D E Shaw D. E. Shaw | 4,350,995 | $757,247,170 | -24% | 0.42% |
| 4. | Orbis Investment Management William B. Gray | 4,179,957 | $727,479,716 | +29% | 3.05% |
| 5. | Millennium Management Israel Englander | 1,311,654 | $228,280,262 | -44% | 0.1% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $66.35 | 1,130 | $74,975.50 | 3,025 | 2025-05-21 | Filing | |
| $66.87 | 1,895 | $126,718.65 | 1,895 | 2025-05-20 | Filing | |
| $19.29 | 10,000 | $192,900.00 | 10,000 | 2023-05-15 | Filing | |
| $19.29 | 10,000 | $192,900.00 | 298,615 | 2023-05-15 | Filing | |
| $17.70 | 10,000 | $177,000.00 | 15,900 | 2022-11-01 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $164.95 | 62,344 | $10,283,642.80 | 106,810 | 2026-04-01 | Filing | |
| $164.11 | 19,001 | $3,118,254.11 | 169,154 | 2026-04-01 | Filing | |
| $163.18 | 6,715 | $1,095,753.70 | 188,155 | 2026-04-01 | Filing | |
| $150.98 | 19,638 | $2,964,945.24 | 51,871 | 2026-03-30 | Filing | |
| $144.11 | 4,533 | $653,250.63 | 301,185 | 2026-03-19 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 2,162 | $356,427 | 0% | |
| 2. | 2,141 | $350,096 | 0.04% | |
| 3. | 1,814 | $296,625 | 0.01% | |
| 4. | 1,165 | $190,458 | 0% | |
| 5. | 662 | $108,250 | 0.03% |
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