| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Redmile Group Jeremy Green | 12,629,737 | $1,148,422 | 13.9% | |
| 2. | Casdin Capital Eli Casdin | 3,050,000 | $277,337 | 8.21% | |
| 3. | Farallon Capital Thomas Steyer | 3,000,000 | $272,790 | -4% | 1.77% |
| 4. | ARK Investment Management Catherine D. Wood | 2,901,700 | $263,852 | +102% | 0.7% |
| 5. | Citadel Investment Group Ken Griffin | 1,108,640 | $100,809 | -58% | 0.02% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $85.50 | 327,485 | Large Shareholder, Director | 12,957,222 | 2021-01-08 | Filing | |
| $28.31 | 1,412,928 | Large Shareholder, Director | 12,629,737 | 2020-06-11 | Filing | |
| $17.50 | 857,143 | Large Shareholder, Director | 11,216,809 | 2019-09-16 | Filing | |
| $13.50 | 3,703,704 | Large Shareholder, Director | 10,359,666 | 2018-09-25 | Filing | |
| $2.66 | 37,593 | Officer | 37,593 | 2016-11-23 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $103.16 | 5,547 | Officer, Director | 393,793 | 2021-02-18 | Filing | |
| $102.26 | 8,602 | Officer, Director | 399,340 | 2021-02-18 | Filing | |
| $101.42 | 2,602 | Officer, Director | 407,942 | 2021-02-18 | Filing | |
| $100.48 | 1,848 | Officer, Director | 410,544 | 2021-02-18 | Filing | |
| $99.08 | 1,401 | Officer, Director | 412,392 | 2021-02-18 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 410,425 | $37,319,945 | 0.01% | |
| 2. | 11,773 | $1,070,519 | 0% | |
| 3. | 10,959 | $997,000 | 0.15% | |
| 4. | 7,604,904 | $691,514 | 0.06% | |
| 5. | 6,671,541 | $606,642 | 0.02% |
