| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 7,959,538 | $162,931,743 | 3.83% | |
| 2. | Commodore Capital Egen Atkinson And Michael Kramarz | 4,692,809 | $96,061,800 | 4.69% | |
| 3. | Polar Capital Brian Ashford-Russell And Tim Woolley | 3,095,007 | $63,354,793 | +2% | 0.3% |
| 4. | Citadel Investment Group Ken Griffin | 1,160,503 | $23,755,496 | -22% | 0% |
| 5. | Vestal Point Capital Ryan Wilder | 1,160,000 | $23,745,200 | +364% | 1.07% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $22.07 | 622 | $13,723.27 | 718,749 | 2023-02-23 | Filing | |
| $5.11 | 23,565 | $120,487.85 | 2,872,513 | 2023-02-22 | Filing | |
| $5.25 | 8,194 | $43,010.31 | 2,848,948 | 2023-02-21 | Filing | |
| $4.00 | 629,297 | $2,516,055.27 | 3,880,021 | 2023-01-03 | Filing | |
| $3.93 | 19,299 | $75,845.07 | 3,250,724 | 2022-12-09 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $21.78 | 1,705 | $37,133.88 | 263,311 | 2025-12-08 | Filing | |
| $20.76 | 4,958 | $102,938.99 | 265,016 | 2025-12-08 | Filing | |
| $23.09 | 492 | $11,360.77 | 902,688 | 2025-11-19 | Filing | |
| $22.30 | 12,008 | $267,794.01 | 903,180 | 2025-11-19 | Filing | |
| $21.82 | 12,500 | $272,738.75 | 890,392 | 2025-11-17 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 7,129,196 | $145,934,642 | 0.01% | |
| 2. | 3,711,444 | $75,973,259 | 6.84% | |
| 3. | 3,518,524 | $72,024,186 | 0% | |
| 4. | 3,226,331 | $66,042,996 | 3.72% | |
| 5. | 2,553,014 | $52,260,198 | 0% |
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