| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Casdin Capital Eli Casdin | 1,610,000 | $91,931 | +23% | 2.73% |
| 2. | Two Sigma Advisors John Overdeck And David Siegel | 451,300 | $25,769 | +73% | 0.07% |
| 3. | Euclidean Capital Jim Simons | 323,749 | $18,486 | 6.18% | |
| 4. | Marshall Wace LLP Paul Marshall And Ian Wace | 275,926 | $15,755 | 0.07% | |
| 5. | Renaissance Technologies Jim Simons | 265,900 | $15,183 | 0.01% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.00 | 275,000 | Large Shareholder | 19,462,499 | 2017-12-12 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $65.78 | 400 | Director | 132,831 | 2021-07-21 | Filing | |
| $65.24 | 866 | Director | 133,231 | 2021-07-21 | Filing | |
| $64.25 | 400 | Director | 134,097 | 2021-07-21 | Filing | |
| $71.11 | 986 | Director | 134,497 | 2021-06-23 | Filing | |
| $70.20 | 680 | Director | 135,483 | 2021-06-23 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 174,796 | $13,711 | 0.12% | |
| 2. | 63,781 | $5,003 | 0.03% | |
| 3. | 50,860 | $3,989 | 0.01% | |
| 4. | 31,200 | $2,447 | 0% | |
| 5. | 17,200 | $1,349 | 0.1% |
