| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Renaissance Technologies Jim Simons | 5,682,783 | $229,072,983 | -2% | 0.36% |
| 2. | Tang Capital Management Kevin C. Tang | 1,500,000 | $60,465,000 | +857% | 3.07% |
| 3. | D E Shaw D. E. Shaw | 1,181,348 | $47,620,138 | +597% | 0.03% |
| 4. | BioImpact Capital Mpm Capital | 985,700 | $39,733,567 | 3.07% | |
| 5. | Two Sigma Advisors John Overdeck And David Siegel | 945,884 | $38,128,584 | 0.03% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $33.56 | 24,218 | $812,836.00 | 1,146,631 | 2026-03-17 | Filing | |
| $33.00 | 75,782 | $2,500,972.72 | 1,122,413 | 2026-03-17 | Filing | |
| $21.53 | 100,000 | $2,153,000.00 | 3,308,303 | 2021-06-11 | Filing | |
| $21.53 | 50,000 | $1,076,500.00 | 1,046,838 | 2021-06-11 | Filing | |
| $22.64 | 68 | $1,539.52 | 3,208,303 | 2020-12-01 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $89.49 | 1,978 | $177,007.46 | 1,084,543 | 2026-07-15 | Filing | |
| $88.81 | 2,974 | $264,122.43 | 1,086,521 | 2026-07-15 | Filing | |
| $87.74 | 3,969 | $348,222.60 | 1,089,495 | 2026-07-15 | Filing | |
| $86.78 | 1,079 | $93,633.14 | 1,093,464 | 2026-07-15 | Filing | |
| $89.43 | 101 | $9,032.25 | 16,130 | 2026-07-15 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 440,264 | $38,280,954 | 0.29% | |
| 2. | 324,876 | $28,247,969 | 1.47% | |
| 3. | 98,803 | $8,590,921 | 0.01% | |
| 4. | 84,041 | $7,307,365 | 1.46% | |
| 5. | 83,110 | $7,226,414 | 0.15% |
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