| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Opaleye Management James A. Silverman | 600,000 | $3,120 | 0.89% | |
| 2. | Redmile Group Jeremy Green | 3,728,690 | $19,389 | -3% | 0.74% |
| 3. | Sessa Capital John Petry | 940,291 | $4,890 | 0.51% | |
| 4. | Aisling Capital Dennis Purcell | 472,943 | $2,459 | 0.43% | |
| 5. | Armistice Capital Steven Boyd | 1,031,200 | $5,362 | 0.41% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.50 | 10,000 | Officer, Director | 99,685 | 2018-06-12 | Filing | |
| $4.47 | 22,417 | Officer, Director | 281,238 | 2016-08-29 | Filing | |
| $3.70 | 50,000 | Director | 381,440 | 2016-06-24 | Filing | |
| $3.69 | 13,188 | Officer, Director | 258,821 | 2016-06-24 | Filing | |
| $4.53 | 10,000 | Director | 331,440 | 2016-05-13 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.81 | 15,000 | Director | 108,167 | 2018-05-18 | Filing | |
| $4.80 | 30,000 | Director | 123,167 | 2018-05-17 | Filing | |
| $4.79 | 30,000 | Director | 153,167 | 2018-05-16 | Filing | |
| $4.69 | 30,000 | Director | 183,167 | 2018-05-15 | Filing | |
| $4.67 | 22,553 | Director | 213,167 | 2018-05-14 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 342,000 | $1,778 | 0.21% | |
| 2. | 3,144,221 | $16,350 | 0.16% | |
| 3. | 28,245 | $147 | 0.12% | |
| 4. | 16,300 | $85 | 0.06% | |
| 5. | 24,000 | $125 | 0.05% |
