| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Opaleye Management James A. Silverman | 600,000 | $2,778 | -58% | 0.88% |
| 2. | Redmile Group Jeremy Green | 3,832,778 | $17,746 | -10% | 0.77% |
| 3. | Sessa Capital John Petry | 940,291 | $4,354 | 0.51% | |
| 4. | Aisling Capital Dennis Purcell | 472,943 | $2,190 | 0.43% | |
| 5. | Ascend Capital Malcolm Fairbairn | 699,664 | $3,240 | +97% | 0.12% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.47 | 22,417 | Officer, Director | 281,238 | 2016-08-29 | Filing | |
| $3.70 | 50,000 | Director | 381,440 | 2016-06-24 | Filing | |
| $3.69 | 13,188 | Officer, Director | 258,821 | 2016-06-24 | Filing | |
| $4.53 | 10,000 | Director | 331,440 | 2016-05-13 | Filing | |
| $4.85 | 24,200 | Director | 321,440 | 2016-05-11 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.47 | 19,833 | Officer | 60,996 | 2017-12-01 | Filing | |
| $4.52 | 20,291 | Director | 268,535 | 2016-12-28 | Filing | |
| $4.67 | 4,000 | Director | 288,826 | 2016-12-28 | Filing | |
| $4.65 | 3,636 | Director | 292,826 | 2016-12-27 | Filing | |
| $4.68 | 72,073 | Director | 296,462 | 2016-12-27 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 342,000 | $1,778 | 0.21% | |
| 2. | 16,300 | $85 | 0.06% | |
| 3. | 94,980 | $494 | 0% |
