| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Camber Capital Management Stephen Dubois | 1,647,677 | $53,286 | +34% | 2.05% |
| 2. | DAFNA Capital Management Nathan Fischel | 59,200 | $1,915 | 0.89% | |
| 3. | Consonance Capital Management Mitchell Blutt | 305,235 | $9,871 | -32% | 0.63% |
| 4. | Partner Fund Management Christopher Medlock James | 1,230,921 | $39,808 | +50% | 0.62% |
| 5. | Bridger Management Roberto Mignone | 352,783 | $11,409 | 0.61% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $38.39 | 2,500 | Officer, Director | 278,362 | 2018-08-29 | Filing | |
| $7.55 | 250,000 | Large Shareholder | 4,100,000 | 2016-02-23 | Filing | |
| $9.30 | 2,700 | Officer, Director | 9,533 | 2016-01-25 | Filing | |
| $22.74 | 2,500 | Director | 59,645 | 2015-08-12 | Filing | |
| $22.98 | 2,174 | Director | 2,174 | 2015-08-07 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $37.54 | 971 | Officer | 23,229 | 2018-08-17 | Filing | |
| $37.56 | 1,344 | Officer | 49,469 | 2018-08-17 | Filing | |
| $37.56 | 2,147 | Officer | 87,705 | 2018-08-17 | Filing | |
| $37.52 | 862 | Officer | 22,634 | 2018-08-17 | Filing | |
| $30.09 | 278 | Officer | 24,200 | 2018-05-18 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 487,207 | $15,756 | 2.45% | |
| 2. | 68,350 | $2,210 | 1.58% | |
| 3. | 54,896 | $1,775 | 1.25% | |
| 4. | 2,786,053 | $90,101 | 0.92% | |
| 5. | 2,416,160 | $78,139 | 0.75% |
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