| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | DAFNA Capital Management Nathan Fischel | 143,611 | $1,867 | +28% | 0.92% |
| 2. | Millennium Management Israel Englander | 314,345 | $4,086 | -3% | 0% |
| 3. | Opaleye Management James A. Silverman | 0 | $0 | 0% | |
| 4. | D E Shaw D. E. Shaw | 0 | $0 | 0% | |
| 5. | 36,700 | $477 | -54% | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $18.19 | 500,000 | Large Shareholder | 3,568,057 | 2017-03-31 | Filing | |
| $4.93 | 247,727 | Director | 3,068,057 | 2016-03-17 | Filing | |
| $4.78 | 152,273 | Director | 2,820,330 | 2016-03-16 | Filing | |
| $4.93 | 247,727 | Large Shareholder | 3,068,057 | 2016-03-17 | Filing | |
| $4.78 | 152,273 | Large Shareholder | 2,820,330 | 2016-03-16 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.99 | 20,000 | Officer, Director | 953,788 | 2019-02-01 | Filing | |
| $15.04 | 5,000 | Officer, Director | 973,788 | 2019-01-04 | Filing | |
| $13.13 | 15,000 | Officer, Director | 978,788 | 2019-01-02 | Filing | |
| $12.53 | 4,300 | Officer | 146,479 | 2018-12-28 | Filing | |
| $12.51 | 3,100 | Officer | 6,386 | 2018-12-28 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,568,057 | $46,385 | 68.06% | |
| 2. | 1,204,654 | $15,661 | 3.78% | |
| 3. | 20,319 | $264 | 1.7% | |
| 4. | 303,930 | $3,951 | 0.44% | |
| 5. | 600,342 | $7,624 | 0.35% |
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