| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 10,900,000 | $375,941,000 | +3% | 4.86% |
| 2. | Slate Path Capital David Greenspan | 4,982,000 | $171,829,180 | -5% | 2.66% |
| 3. | Siren L.L.C. Raymond Debbane | 2,669,880 | $92,084,161 | 3.6% | |
| 4. | Driehaus Capital Richard Driehaus | 2,099,398 | $72,408,237 | 0.52% | |
| 5. | Arrowstreet Capital Peter Rathjens, Bruce Clarke And John Campbell | 2,081,689 | $71,797,454 | +3143% | 0.05% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $22.00 | 500 | $11,000.00 | 36,080 | 2024-04-18 | Filing | |
| $25.00 | 500 | $12,500.00 | 35,580 | 2024-04-10 | Filing | |
| $27.34 | 150 | $4,101.00 | 35,080 | 2024-04-02 | Filing | |
| $27.50 | 850 | $23,375.00 | 34,930 | 2024-03-26 | Filing | |
| $28.00 | 400 | $11,200.00 | 34,080 | 2024-03-22 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $35.00 | 20,000 | $700,000.00 | 212,122 | 2025-10-01 | Filing | |
| $30.00 | 15,000 | $450,000.00 | 232,122 | 2025-09-12 | Filing | |
| $25.00 | 15,000 | $375,000.00 | 247,122 | 2025-09-02 | Filing | |
| $20.00 | 9,389 | $187,780.00 | 262,122 | 2025-08-15 | Filing | |
| $20.00 | 611 | $12,220.00 | 271,511 | 2025-08-13 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 20,224,825 | $697,554,214 | 0.01% | |
| 2. | 16,035,870 | $553,077,156 | 0.01% | |
| 3. | 6,397,364 | $220,645,084 | 0.01% | |
| 4. | 5,759,830 | $198,656,549 | 0.01% | |
| 5. | 3,131,042 | $108,008,198 | 0.01% |
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